Hitting at least 3 enemies with an attack, increases your cleave by 140-200% for 2 seconds.
2.5-4% Bonus Critical Chance on Chained Hit. Stacks 5 times.
1-4% Toughness for every 10% of magazine spent during continuous fire. Stacks 5 times.
Suppress Enemies within 5-8 Radius on Close Range Kill.
Most of the gear choices are pretty interchangeable, but a melee with good cleave and a quickdraw gun are your best bets.
Don't forget to dodge, life leech only goes so far :)