Man I Love Chems
 Hive Scum Build - Warhammer 40k: Darktide 

One of the most winding talent builds I've made, and one of my new favorite playstyles. Made this to be able to more easily show my friends what I'm talking about. This build will shred through any armor and isn't bad against hordes either. Switch to the bonesaw after stacking up Chem on something big and keep re-applying it while they melt. The emphasis on crit bonuses is due to the fact that the Needler applies a bonus stack on crit.

The ability choice is somewhat of a flex pick, however I chose Desperado because of the Rending buff and the easy ranged immunity, the latter of which frees up the option to use a more offensive blessing on the Needler. For the capstone, as appealing as it might seem, I can't really recommend Vulture's Mark because in practice, your kills will get stolen a lot by someone finishing off the targets you softened. Spamming your Stimm for more Rending uptime is just a good habit to get into anyway.

You could potentially run Blackout grenades with Pocket Toxin and/or Cheap Shots for good effect, and functionally remove the need to compete for grenade pickups, but you'd have to free up a point or two somewhere else, probably dropping the bonus crit from dodging and either the melee toughness gain or the Stimm duration.

Take my Curio suggestions with a huge grain of salt, imo you're allowed a lot of preference there.