Psyker
This weapon Blocks both Melee and Ranged attacks. Additionally, Block Cost is reduced by 22.5-30%.
Quell 2-5% of Peril on Repeated Weak Spot Hit.
Target receives up to 2-8 Stacks of 2.5% Brittleness, scaling with charge time of Secondary Attack. Debuff lasts for 5 seconds and can have a maximum of 16 stacks.
-8.5--5.5% Charge Time on Chained Secondary Attack. Stacks 3 times.
If Perk not selected you can take with anything that floats your boat.
For instance if you carry Grimoires, you can take resistance against them.
Just match it with you gameplay (and your luck with gear drop).
This build focus on Building Stacks of "Emporered Psionics" with Trauma Staff Short/Mid range so you can use Brain Rupture on Long range targets.
With the Trauma Staff and Rupture it is Fairly easy to kill anything not an Ogryns, a Mutants or a Hounds.
Each Elite or Special Kill will place DOTs of Fire with "Perilous Combustion" and they will be roaming around with "Wildfire".
Your melee weapon is an Ilisi Sword for Additional Fire DOTs roaming around when you need to an "Exorcist" Will provide an active Quelling method if needed (R is a passive way dealing no damages).
"Telekine Shield" will be your main way of dealing with Hounds, Mutants and ranged enemies projectiles.
This build generate Toughness while Generating or Quelling Peril and when you Kill with Warp damages(Charged Ilisi Sword attack and fire DOTs also count as Warp damages).