H40 Pickaxe Ogryn
 Ogryn Build - Warhammer 40k: Darktide 

This is not a difficult build:

You will be using your primary 95% of the time.

Horde Clear

Pattern is: 

- Pure Horde Heavy attack, light attack. Just that. 

- Mixed Horde: spam heavies. First one will be for the poxwalkers. The second one use it to bonk the specials/elites.

Another useful combo is to start with a push attack, then light, then start the combo

Boss damage/ogryns

Use the pull (special attack) followed by a charged heavy. Chain those two for maximum result, remember to look for Crunch! stacks before going off.

The stubber 

This gun, on a weakspot hit with Opening Salvo active, will oneshot any ranged specialist and, most notably, oneshot a sniper on almost any shot. 

Regarding the second blessing slot: I runOverwhelming Fire to help with Reaper, but in all honesty my experience has all blessings on the gun to be quite lackluster. 

Many run Surgical, but that encourages you to keep aiming downsights, which contrasts quite a bit with your role as a frontliner. Ideally you want to swap weapons to snipe a particular specialist that is giving you bullsheisse; chop his head off, then swap back and keep controlling the horde: killing bombers, flamers and snipers is not your job. 

Blaze Away gives it a similar mechanic to surgical with the same effect as overwhelming fire. This makes it generally worse at single target killing. Only case it gets better is when fighting at range versus a gunner patrol. Not exactly what an ogryn wants to do ideally.

BIG BOOM

The granade staggers everything in a large radius useful for risky revives, to relieve pressure in tight corners or, most importantly soloing rituals. 

Cultists are place in a cirular radius around the deamonhost a well placed granade can immediately end the ritual. Aim for it to land under the host's feet, this allows for long range snipes or solo action, since you have Valuable Distraction be sure to use it, the damage amplification allows for less precise throws, Remember that you can also perform and underhand throw that works way better at short range.

When you taunt the horde you have to put yourself between that and the team, otherwise you will pull it into your teammates and swarm them. 

Use the taunt to stagger bosses, interrupt crusher's attack animations, try and use it every time it is out of Cooldown.